Initial human testing of an investigational vaccine to prevent Ebola virus disease will begin next week by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
The early-stage trial will begin initial human testing of a vaccine co-developed by NIAID and GlaxoSmithKline (GSK) and will evaluate the experimental vaccine’s safety and ability to generate an immune system response in healthy adults.
The pace of human safety testing for experimental Ebola vaccines has been expedited in response to the ongoing Ebola virus outbreak in West Africa.
Testing will take place at the NIH Clinical Center in Bethesda, Maryland.
The study is the first of several Phase 1 clinical trials that will examine the investigational NIAID/GSK Ebola vaccine and an experimental Ebola vaccine developed by the Public Health Agency of Canada and licensed to NewLink Genetics Corp.
The others are to launch in the fall. These trials are conducted in healthy adults who are not infected with Ebola virus to determine if the vaccine is safe and induces an adequate immune response.Continue reading →
Experts have long believed that when the risk of a disease is high, people are more likely to accept a vaccine to prevent that disease. But recent research suggests that might not be uniformly true. Dr. Elizabeth Wolf, an investigator in Seattle Children’s Research Institute’s Center for Child Health, Behavior and Development, led a study that determined Washington’s recent pertussis (whooping cough) epidemic did not influence the number of infants who were vaccinated against the disease.
Washington has had more measles cases so far this year than in the past five years combined. State health officials are sounding the alarm to remind people that vaccination is the best protection against the spread of this serious disease.
From the Washington State Department of Health
So far in 2014 there have been 27 measles cases in Washington, up from the five reported in 2013.
The most recent cases reported in the past month have been in King County (11 confirmed cases) and Pierce County (two confirmed cases).
This is the third measles outbreak in our state this year and the number of cases so far is the highest reported in any year since 1996.Continue reading →
Cases of measles in the U.S. reached a 20-year high during the first five months of this year. The majority of cases, health officials say, have been associated with unvaccinated Americans who contracted the virus while traveling to other countries.
A total of 288 measles cases were reported across 18 states between Jan. 1 and May 23, according to the Centers for Disease Control and Prevention (CDC), the largest number for the first five months of any year since 1994 and the most seen compared with year-end totals since 1996.Continue reading →
Kitsap County resident confirmed with measles; exposure likely in San Juan County
From the Washington State Department of Health:
April 11, 2014 - Measles continues to spread in Washington as cases in San Juan County have extended to a Kitsap County resident. A man in his 40s from Kitsap visited several places in Friday Harbor, including a restaurant where a contagious San Juan County man was at the same time.
San Juan County’s case count is now five, and Kitsap County has one. In Whatcom County, the case count remains at six. Continue reading →
The flu hit younger- and middle-age adults hard this season, the Centers for Disease Control and Prevention (CDC) reported Thursday.
While the elderly tend to be most vulnerable to influenza, a large majority of those hospitalized with the flu this season, 61%, were people age 18-64 — a big jump from what was seen during the past three flu seasons in which people from this age group made up only about 35 percent of hospitalizations.
Influenza deaths this season are following a similar pattern, with people 25 years to 64 years of age accounting for about 60 percent of flu deaths compared with 18 percent, 30 percent, and 47 percent for the three previous seasons. Continue reading →